Cy5 Maleimide (Solution)

Cyanine-based fluorescent dye reagent for protein, antibody and small-molecule labeling applications.

Size: 100 µL

Concentration: 10 mM

Solvent: DMSO

Dry Ice: No

Hazardous: No

Shipping: Room temperature

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Description

Cy5 maleimide (solution) is a cyanine (Cy) dye. Cyanine compounds are characterized by long-wavelength absorption and emission, adjustable spectral properties, high extinction coefficients, good water solubility and relatively simple synthesis.

Cy dyes are commonly used for labeling proteins, antibodies and small-molecule compounds. Protein and antibody labeling can be performed through a simple mixing reaction.

Solvent and concentration: DMSO, 10 mM

Product Information

CAS Number	1437796-65-0
Target	DNA Stain; Fluorescent Dye
Related Pathways	Cell Cycle/DNA Damage; Others
Field of Research	Others
Molecular Formula	C38H45ClN4O3
Molecular Weight	641.25
SMILES	O=C(NCCN(C1=O)C(C=C1)=O)CCCCCN(/C2=C/C=C/C=C/C(C3(C)C)=[N+]\(C4=CC=CC=C34)C)C5=CC=CC=C5C2(C)C.[Cl-]

Scientific Category: Dye Reagents | Clinical Information: No Development Reported

References & Citations

[1] Maeda K, et al. Cy5 maleimide labelling for sensitive detection of free thiols in native protein extracts: identification of seed proteins targeted by barley thioredoxin h isoforms. Biochem J. 2004 Mar 1;378 (Pt 2):497-507.

[2] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108.

[3] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029

Molecular Visualization · PubChem

Cy5 Maleimide

Explore the chemical structure of Cy5 maleimide in two dimensions and interact with its three-dimensional molecular model. Rotate, zoom and inspect the molecular geometry.

PubChem Compound ID 91757870

Molecular Formula Loading...

Molecular Weight Loading...

2D Chemical Structure

Two-dimensional molecular diagram from PubChem

Loading the chemical diagram...

3D Molecular Structure

Interactive 3D conformer · Drag to rotate · Scroll to zoom

Loading the 3D molecular model...

Data source: PubChem - Cy5 Maleimide, CID 91757870
Molecular data are requested directly from the PubChem PUG REST API. The PubChem record contains a 2D structure and a 3D conformer associated with the parent compound.